Description 

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School on 3D electron diffraction techniques and how to apply them for structure determination of nano/microcrystals too small for single-crystal X-ray diffraction. The topics will cover inorganic, organic and biological compounds. The school will include both lectures and practical sessions on computers.

List of topics to be covered:

• The development of various 3D electron diffraction techniques – a historical perspective.

• Introduction to Transmission Electron Microscopy and electron diffraction.

• Electron diffraction (SAED, CBED, PED) and space group determination.

• Sample preparation for both materials and life sciences.

• 3D ED Data collection.

• 3D ED Data Processing and data merging including practical demo labs.

• Methods for phasing diffraction data – small molecules and macromolecules.

• Practical demo labs for structure solution and refinement with 3D ED data.

• Dynamical refinement (PEDT/cRED).

• New developments in 3D electron crystallography.

• The school also includes poster presentations and company presentations.

• The last day will include a round table discussion.